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Saturday, May 9, 2020 | History

2 edition of Developing QALYs from condition-specific outcome measures found in the catalog.

Developing QALYs from condition-specific outcome measures

John A. Cairns

Developing QALYs from condition-specific outcome measures

by John A. Cairns

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Published by Health Economics Research Unit, University of Aberdeen in Aberdeen .
Written in English


Edition Notes

Statementby John Cairns, Kathy Johnston and Lynda McKenzie.
SeriesDiscussion paper / Health Economics Research Unit -- no.14/91
ContributionsJohnston, Kathy., McKenzie, Lynda., University of Aberdeen. Health Economics Research Unit.
The Physical Object
Pagination30p. ;
Number of Pages30
ID Numbers
Open LibraryOL20859440M

I think here are two resources from the National Institute for Health Research, a review of the health status measures from , and then developing testing methods for driving the preference measures of health from condition specific measures. These are two terrific resources. Visit to get more information about this book, to buy it in print, or to download it as a free PDF.

  To address these issues, by promoting a systematic approach to study identification, critical appraisal, and appropriate use, we are developing the Health Utility Book (HUB). The HUB consists of an HSUV registry, a quality assessment tool for health utility studies, and a checklist for interpreting their use in by: 2. these measures is most appropriate for regulatory analysis. We then describe and evaluate each approach in more detail. The subsequent sections of this chapter first briefly review the single-dimension measures common in statistical reporting systems and epidemiological studies, including case reporting of illness or injury, preventable deaths, and life years lost.

  Outcome measures that are reported by patient-defined endpoints, such as health-related quality of life and satisfaction with care, and outcome-linked process measures have had much more limited application. Each of these classes of measures, with illustrative applications where available, is discussed in the following by: Addressing the Criteria for the Set. To ensure that the core measure set would be as relevant, useful, and effective as possible for a broad range of stakeholders, the Committee focused on identifying measures for the health influences, characteristics, and interventions that matter most in the domains of healthy people, quality of care, costs of care, and people’s engagement in .


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Developing QALYs from condition-specific outcome measures by John A. Cairns Download PDF EPUB FB2

Cincinnati Children's Hospital Medical Center is committed to ensuring that our patients achieve the best possible health outcomes. Fundamental to reaching this goal is the use of condition-specific measurement where we define and report disease-specific health outcomes such as remission rates, physical functioning and health-related quality of life.

Introduction. Economic evaluation has become widely used as a method for assessing the value for money of health intervention programmes in Australia and overseas. 1 The most prevalent form of economic evaluation is cost utility analysis, which compares interventions in terms of their incremental cost per quality-adjusted life year (QALY).

The Cited by: 5. Quality adjusted life years (QALYs) offer a measure of value which is advantageous for health technology appraisal (HTA). As a composite measure, combining length of life and preference-based self-reported health related quality of life (HRQoL), the application of QALYs, and the assessment of value, in oncology and cancer care can be by: There are a wide number of outcome measures covering most health care states.

Before developing a new measure a review (preferably systematic) of the available outcome measures should be undertaken. For an example, we will consider a randomised trial of HRT. It was deemed that a relevant outcome to be measured should be sexual functioning.

Mean generic QALYs (estimated using the EQ-5D-3L) were significantly lower than condition-specific QALYs (estimated using the EORTC-8D) ( vs. 40 Direct elicitation methods, generic preference-based measures, and condition-specific measures were used to evaluate HRQoL.

The EQ-5D-3L, regarded as. Health policy in the UK and elsewhere is prioritising patient empowerment and patient evaluations of healthcare.

Patient reported outcome measures now take centre-stage in implementing strategies to increase patient empowerment. This article argues for consideration of patient empowerment itself as a directly measurable patient reported outcome for chronic Cited by:   Developing PRO measures: benefits and limitations.

The processes involved in developing PRO measures can be summarised in four steps, as shown in Figure 1. 4 These processes are refined and strengthened by the incorporation of feedback at each step, making the outcome of the process more reliable and by: 8.

With an ageing population, the number of people with dementia is rising. The economic impact on the health care system is considerable and new treatment methods and approaches to dementia care must be cost effective. Economic evaluation requires valid patient reported outcome measures, and this study aims to develop a dementia-specific health state Cited by: 3.

Condition-specific preference-based measures, developed from previously validated disease-specific patient-reported outcomes instruments, may. End-of-life (EoL) care 1 is increasingly used as a generic term in preference to palliative care or terminal care, particularly with reference to individuals with chronic disease, who are resident in community and long-term care (LTC) settings.

This review evaluates studies based on patient reported outcome measures (PROMS) of quality of EoL care across all health-care settings. This chapter provides an overview of considerations for the development of outcome measures for observational comparative effectiveness research (CER) studies, describes implications of the proposed outcomes for study design, and enumerates issues of bias that may arise in incorporating the ascertainment of outcomes into observational research, and means of Cited by: Mortality and Life Expectancy.

The oldest and simplest measures of population health are death records. These were used, for example, to calculate the impact in excess deaths of the great plague of – in London (Champion, ).With the decline in deaths from infectious disease in the developed world, crude death rates are primarily determined by the.

Background. This paper aimed to identify condition-specific patient-reported outcome measures used in clinical trials among people with wrist osteoarthritis and summarise empirical peer-reviewed evidence supporting their reliability, validity, and responsiveness to change. Methods. A systematic review of randomised controlled trials among people with wrist osteoarthritis was Cited by: A.

Tsuchiya, P. Evans, A. Keetharuth, Use of generic and condition-specific measures of health-related quality of life in NICE decision-making:. Outcome Measures in Cancer: Do disease specific instruments offer greater sensitivity than generic instruments.

Paula Lorgelly Deputy Director, OHE Visiting Professor, Division of Cancer Studies, King’s College London C2E2 Rounds 5th July Outcome Measures in Cancer: Do disease specific instruments offer greater sensitivity than generic. A literature review of the nine most widely used, condition-specific, self-administered assessment questionnaires for low back pain has been undertaken.

General and historic aspects, reliability, responsiveness and minimum clinically important difference, external validity, floor and ceiling effects and available languages were analysed for the nine most-used Cited by:   Utility scores are used to estimate Quality Adjusted Life Years (QALYs), applied in determining the cost-effectiveness of health care interventions.

In studies where no preference based measures are collected, indirect methods have been developed to estimate utilities from clinical instruments. The aim of this study was to evaluate a published method of estimating Cited by:   Introduction Generic instruments for assessing health-related quality of life may lack the sensitivity to detect changes in health specific to certain conditions, such as dementia.

The Quality of Life in Alzheimer’s Disease (QOL-AD) is a widely used and well-validated condition-specific instrument for assessing health-related quality of life for people living with Cited by: 5.

Hip and knee osteoarthritis is a common cause of pain and disability, which can be improved by exercise interventions. However, regular exercise is uncommon in this group because the low physical activity level in the general population is probably reduced even further by pain related fear of movement.

The best method of encouraging increased activity in this Cited by: 6. Focusing on health as an outcome measure is likely to underestimate the impact of many public health interventions. This paper provides a review of outcome measures in public health; and describes the benefits of using the capability approach as a means to developing an all encompassing outcome by:   The Short-Form 36 (SF) Health Survey is a brief self-administered questionnaire that generates scores across 8 dimensions of health.

It has been found to be reliable, and valid in terms of criteria such as agreement with clinical diagnosis and disease severity, but its underlying values have not been tested against patient preferences.

The SF Cited by: At Cincinnati Children’s, we seek to provide families and providers with the information they need to make the best possible healthcare decisions. Most importantly, we listen to our patients and families and use this information and feedback to develop lasting, positive change in the way we deliver care.

What Quality Measures Tell You.